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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK14
All Species:
31.82
Human Site:
T46
Identified Species:
58.33
UniProt:
Q16539
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16539
NP_001306.1
360
41293
T46
C
A
A
F
D
T
K
T
G
L
R
V
A
V
K
Chimpanzee
Pan troglodytes
Q95NE7
360
41475
T46
C
A
A
F
D
T
K
T
G
L
R
V
A
V
K
Rhesus Macaque
Macaca mulatta
XP_001112423
329
37756
H46
R
E
L
R
L
L
K
H
M
K
H
E
N
V
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P47811
360
41269
T46
C
A
A
F
D
T
K
T
G
H
R
V
A
V
K
Rat
Rattus norvegicus
P70618
360
41303
T46
C
A
A
F
D
T
K
T
G
H
R
V
A
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232616
360
41440
T46
C
S
A
F
D
T
K
T
G
L
R
V
A
V
K
Frog
Xenopus laevis
P47812
361
41700
T47
C
S
S
F
D
T
R
T
A
L
R
I
A
V
K
Zebra Danio
Brachydanio rerio
Q9DGE2
361
41614
T47
C
S
A
F
D
A
K
T
G
F
K
V
A
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61443
365
42080
T46
C
K
A
V
V
R
G
T
S
T
K
V
A
I
K
Honey Bee
Apis mellifera
XP_395384
360
41360
V46
D
T
K
T
G
Q
K
V
A
I
K
K
L
A
R
Nematode Worm
Caenorhab. elegans
Q17446
377
43900
S57
C
A
A
E
C
T
R
S
G
T
R
V
A
I
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32485
435
48840
Q47
A
T
D
T
L
T
S
Q
P
V
A
I
K
K
I
Red Bread Mold
Neurospora crassa
Q96TL5
358
41225
V46
D
Q
L
T
N
Q
N
V
A
I
K
K
I
M
K
Conservation
Percent
Protein Identity:
100
96.1
89.4
N.A.
N.A.
99.4
98.6
N.A.
N.A.
96.3
88.3
85.8
N.A.
68.4
75
62.8
N.A.
Protein Similarity:
100
97.7
90.8
N.A.
N.A.
99.4
99.1
N.A.
N.A.
98.6
94.7
92.2
N.A.
80.2
85
76.6
N.A.
P-Site Identity:
100
100
13.3
N.A.
N.A.
93.3
93.3
N.A.
N.A.
93.3
66.6
73.3
N.A.
40
6.6
60
N.A.
P-Site Similarity:
100
100
13.3
N.A.
N.A.
93.3
93.3
N.A.
N.A.
100
93.3
86.6
N.A.
53.3
26.6
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
42.9
50.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57.9
69.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
39
62
0
0
8
0
0
24
0
8
0
70
8
0
% A
% Cys:
70
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
0
54
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
54
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
54
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
16
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
16
0
16
8
16
16
% I
% Lys:
0
8
8
0
0
0
62
0
0
8
31
16
8
8
77
% K
% Leu:
0
0
16
0
16
8
0
0
0
31
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
16
0
8
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
8
16
0
0
0
54
0
0
0
8
% R
% Ser:
0
24
8
0
0
0
8
8
8
0
0
0
0
0
0
% S
% Thr:
0
16
0
24
0
62
0
62
0
16
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
16
0
8
0
62
0
62
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _